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The brain has the consistency of firm jelly, and therefore is protectively encased in a thick, bony skull. The brain literally floats in about 150 millilitres (mL. Dopamine produced in the ventral tegmental area flows via the mesolimbic pathway - medial forebrain bundle to the nucleus accumbens in the basal ganglia - corpus. The brain’s mesolimbic dopamine system, its reward pathway, is stimulated by all types of reinforcing stimuli, such as food, sex, and many drugs of abuse, including. Explains the differences between alcohol dependence and alcohol abuse.

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